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Posted 07 Sep 2024

2 min read

An infograhic image showing types of Drug-Resistant TB namely, Multidrug Resistant (MDR) TB which is resistant to aleast Isoniazid and Rifampicin; Extensively Drug Resistant (XDR) TB which is resistant to Isoniazid and Rifampicin plus fluoro-quinolone and at least one of the three injectable second-line drugs; and Totally Drug Resistant (TDR) TB which is resistant to all first-line and second-line TB drugs.

New BPaLM regimen consisting of four drugsBedaquiline, Pretomanid, Linezolid and Moxifloxacin — has proven to be a safe, more effective and quicker treatment option than previous procedures. 

  • Earlier, Pretomanid has been approved & licensed for use in India by CDSCO. 
  • It brings down treatment time to 6 months from earlier duration of 20 months.
  • BPaLM regimen was introduced under National TB Elimination Programme and expected to boost the country’s progress to achieve its national goal of ending TB in India by 2025.

About Tuberculosis

  • An infectious disease that most often affects lungs and is caused by bacillus Mycobacterium tuberculosis bacteria. 
  • Bacillle Calmette-Guerin (BCG) vaccine provides immunity against TB.
  • As per India TB Report 2024, there were 25.52 lakh notified TB patients in 2023. 

Challenges in Tuberculosis Eradication

  • Social Stigma leads to delayed diagnosis; High Treatment Costs, Comorbidities with HIV, diabetes; Lack of diagnostics facility in rural areas etc.

 Other Initiatives taken for Tuberculosis Eradication 

  • Pradhan Mantri TB Mukt Bharat Abhiyan provides additional patient support, augment community involvement.
  • Ni-kshay Mitra ensures additional diagnostic, nutritional, support to those on TB treatment.
  • Nikshay Poshan Yojana provides financial support to TB patients for their nutrition.
  • Tags :
  • Tuberculosis
  • BPaLM regimen
  • National TB Elimination Programme
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