News Today Logo

Posted 15 Nov 2024

2 min read

“PPP plus PPP” is a two-tiered collaboration where India’s public and private sectors unite internally to strengthen healthcare infrastructure while simultaneously engaging with international counterparts.

  • The model was introduced on World Diabetes Day (14th November) which was made a global observation by the UN in 2006 and was first established in 1991 by WHO and International Diabetes Federation (non-profit organisation). 

About Diabetes or Diabetes Mellitus (DM)

  • DM is a chronic, metabolic disease that causes elevated blood glucose levels (hyperglycemia)
  • Symptoms: Loss of glucose through urine and formation of harmful compounds known as ketone bodies. 
    • It can cause serious damage to the heart, blood vessels, eyes, kidneys, and nerves. 
  • Major Types 
    • Type 1 (juvenile diabetes or insulin-dependent diabetes): Autoimmune disorder in which insulin producing cells are destroyed by immune system 
    • Type 2: Most common type and usually occurs in adults. Caused when body becomes resistant to insulin or doesn't make enough insulin.
    • Gestational: Develops during pregnancy
  • Prevalence:  Around 830 million people globally have diabetes (around 212 million in India), the majority living in low-and middle-income countries 
  • Treatment Gap: More than 50% lack treatment. 
    • Around 64 million men and 69 million women with untreated diabetes in India are at high risk of developing associated severe complications. 
  • WHO Target:  To halt the rise in diabetes and obesity by 2025

About Insulin 

  • Insulin is a peptide hormone secreted by β-cells of Pancreas. 
  • It plays a major role in the regulation of glucose homeostasis
    • Insulin acts mainly on hepatocytes and adipocytes (cells of adipose tissue), and enhances cellular glucose uptake and utilisation.
  • Nowadays, recombinant human insulin is mainly produced either in E. coli or Saccharomyces cerevisiae. 

 

  • Tags :
  • Pancreas
  • Diabetes
  • PPP plus PPP
  • Diabetes Mellitus
  • World Diabetes Day
Watch News Today
Width resize handle
Height resize handle

Search Notes

Filter Notes

No notes yet

Create your first note to get started.

No notes found

Try adjusting your search criteria.

Subscribe for Premium Features